陳妙芬
長庚醫療財團法人林口長庚紀念醫院
國語,英語,閩南語 教授
食道癌、乳癌、泌尿道癌、肺癌之光子與質子治療、立體定位放射治療、輻射生物基礎及轉譯研究
陳妙芬看診時間
| 星期一 | 24 小時營業 |
| 星期二 | 24 小時營業 |
| 星期三 | 24 小時營業 |
| 星期四 | 24 小時營業 |
| 星期五 | 24 小時營業 |
| 星期六 | 24 小時營業 |
| 星期日 | 24 小時營業 |
陳妙芬醫師簡介
現職
- 林口長庚醫院放射腫瘤系主任
- 林口長庚醫院放射腫瘤部乳癌與泌尿腫瘤科主治醫師
- 長庚醫院學術組教授級主治醫師
- 長庚大學部定教授
學歷
- 2006 長庚大學臨床醫學研究所博士
- 1995 台北醫學院醫學士
經歷
- 2014~ 長庚大學部定教授
- 2013~ 長庚醫院放射腫瘤科教授級主治醫師
- 2011~2014 長庚大學專任副教授
- 2010~2013 長庚醫院放射腫瘤科副教授級主治醫師
- 2008~2011 長庚大學專任助理教授
- 2007~2010 長庚醫院放射腫瘤科助理教授級主治醫師
學會與認證
- 台灣放射腫瘤學會
論文及期刊發表
- Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma.
Mol Carcinog . 2022 Aug;61(8):787-796
林口長庚紀念醫院 放射腫瘤科 - Prospective Evaluation of Taste Function in Patients With Head and Neck Cancer Receiving Intensity-Modulated Radiotherapy.
JAMA Otolaryngol Head and Neck Surgery. 2022 Jul; 148(7):604-611.
林口長庚紀念醫院 放射腫瘤科 - Effect of 1α,25-Dihydroxyvitamin D3 on the Radiation Response in Prostate Cancer: Association With IL-6 Signaling.
Front Oncol. 2021 May 24;11:619365. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Role of Nutritional Status in the Treatment Outcome for Esophageal Squamous Cell Carcinoma.
Nutrients. 2021 Aug 28;13(9):2997.
林口長庚紀念醫院 放射腫瘤科 - Intracavernous Injection of Autologous Platelet-Rich Plasma Ameliorates Hyperlipidemia-Associated Erectile Dysfunction in a Rat Model.
Sex Med. 2021 Apr;9(2):100317.
林口長庚紀念醫院 放射腫瘤科 - Risk of major adverse cardiovascular events among second-line hormonal therapy for metastatic castration-resistant prostate cancer: A real-world evidence study.
Prostate. 2021 Feb;81(3):194-201. doi: 10.1002/pros.24096
林口長庚紀念醫院 放射腫瘤科 - Survival of Patients with Lung Cancer in the Setting of Liver Cirrhosis: A Multicenter Propensity Score Matching Study.
Cancer Manag Res. 2021 Jun 1;13:4373-4381. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Survival-Weighted Health Profiles in Nasopharyngeal Cancer Patients.
Front Oncol. 2021 Mar 15;11:635667.
林口長庚紀念醫院 放射腫瘤科 - A Retrospective Analysis of Dose Distribution and Toxicity in Patients with Left Breast Cancer Treated with Adjuvant Intensity-Modulated Radiotherapy: Comparison with Three-Dimensional Conformal Radiotherapy.
Cancer Manag Res. 2020;12:9173-9182. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Prognostic Significance of Neoadjuvant Rectal Scores in Preoperative Short-Course Radiotherapy and Long-Course Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
Ann Surg Oncol. 2020 Oct;27(11):4309-4318 (* Co-Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Porphyromonas gingivalis promotes tumor progression in esophageal squamous cell carcinoma.
Cell Oncol (Dordr). 2021 Apr;44(2):373-384. doi: 10.1007/s13402-020-00573-x.
林口長庚紀念醫院 放射腫瘤科 - The Predictive Role of Prostate-Specific Antigen Changes Following Transurethral Resection of the Prostate for Patients with Localized Prostate Cancer.
Cancers (Basel). 2020 Dec 29;13(1):74.
林口長庚紀念醫院 放射腫瘤科 - The Significance of Neutrophil-to-Lymphocyte Ratio and Combined Chemoradiotherapy in Patients Undergoing Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer.
Cancer Manag Res. 2020 Dec 22;12:13125-13135.
林口長庚紀念醫院 放射腫瘤科 - Prognostic Significance of Neoadjuvant Rectal Scores in Preoperative Short-Course Radiotherapy and Long-Course Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
Ann Surg Oncol. 2020 Oct;27(11):4309-4318
林口長庚紀念醫院 放射腫瘤科 - Effect of Tumor Burden on Tumor Aggressiveness and Immune Modulation in Prostate Cancer: Association with IL-6 Signaling.
Cancers (Basel). 2019 Jul 16;11(7). pii: E992. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Long-Term Taste Impairment after Intensity-Modulated Radiotherapy to Treat Head-and-Neck Cancer: Correlations with Glossectomy and the Mean Radiation Dose to the Oral Cavity.
Chem Senses. 2019 May 29;44(5):319-326. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - The prognosis of head and neck squamous cell carcinoma related to immunosuppressive tumor microenvironment regulated by IL-6 signaling.
Oral Oncol. 2019 Apr;91:47-55. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Lung cancer outcome in the setting of chronic kidney disease: Does the glomerular filtration estimation formula matter?
Thorac Cancer. 2019 Feb;10(2):268-276
林口長庚紀念醫院 放射腫瘤科 - The Response of Prostate Cancer to Androgen Deprivation and Irradiation Due to Immune Modulation.
Cancers (Basel). 2018 Dec 26;11(1). pii: E20. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - The Predictive Value of Pretreatment Neutrophil-To-Lymphocyte Ratio in Esophageal Squamous Cell Carcinoma.
Ann Surg Oncol. 2019 Jan;26(1):190-199
林口長庚紀念醫院 放射腫瘤科 - Predictive Value of the Pretreatment Neutrophil-to-Lymphocyte Ratio in Head and Neck Squamous Cell Carcinoma.
J Clin Med. 2018 Sep 20;7(10). pii: E294.
林口長庚紀念醫院 放射腫瘤科 - Predictive Value of CD44 in Muscle-Invasive Bladder Cancer and Its Relationship with IL-6 Signaling.
Ann Surg Oncol. 2018; 25(12):3518-3526. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line.
Anticancer Res. 2018 Sep;38(9):5183-5192.
林口長庚紀念醫院 放射腫瘤科 - Epigenetic therapy regulates the expression of ALDH1 and immunologic response: Relevance to the prognosis of oral cancer.
Oral Oncol. 2017; 73:88-96. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Cystectomy for bladder cancer in elderly patients is not associated with increased 30- and 90-day mortality or readmission, length of stay, and cost: propensity score matching using a population database.
Cancer Manag Res. 2018 May 31;10:1413-1418.
林口長庚紀念醫院 放射腫瘤科 - Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment.
Mol Carcinog. 2018 Jan; 57(1):78-88 (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Survival benefit of surgery to patients with esophageal squamous cell carcinoma.
Sci Rep. 2017 Apr 6;7:46139
林口長庚紀念醫院 放射腫瘤科 - Impact of CD44 expression on radiation response for bladder cancer.
J Cancer. 2017 Apr 9;8(7):1137-1144 (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Inflammation-induced myeloid-derived suppressor cells associated with squamous cell carcinoma of the head and neck.
Head Neck. 2017;39(2):347-355. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Is chronic kidney disease an adverse factor in lung cancer clinical outcome? A propensity score matching study.
Thorac Cancer. 2017 Mar;8(2):106-113.
林口長庚紀念醫院 放射腫瘤科 - To Operate or Not: Prediction of 3-Month Postoperative Mortality in Geriatric Cancer Patients.
J Cancer. 2016 Jan 1;7(1):14-21.
林口長庚紀念醫院 放射腫瘤科 - he role of PD-L1 in the radiation response and prognosis for esophageal squamous cell carcinoma related to IL-6 and T-cell immunosuppression.
Oncotarget. 2016 Feb 16;7(7):7913-24.
林口長庚紀念醫院 放射腫瘤科 - The role of PD-L1 in the radiation response and clinical outcome for bladder cancer.
Sci Rep. 2016 Jan 25;6:19740. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Identification of High-Risk Subgroups of Patients With Oral Cavity Cancer in Need of Postoperative Adjuvant Radiotherapy or Chemo-Radiotherapy.
Medicine (Baltimore). 2016 May;95(22):e3770. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - 1α,25- Dihydroxyvitamin D3 Inhibits Esophageal Squamous Cell Carcinoma Progression by Reducing IL6 Signaling.
Mol Cancer Ther. 2015 Jun;14(6):1365-75. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Androgen deprivation increases the risk of fracture in prostate cancer patients: a population-based study in Chinese patients.
Osteoporos Int. 2015 Sep;26(9):2281-90. (* Co-corresponding author)
林口長庚紀念醫院 放射腫瘤科 - The Efficacy of Postoperative Adjuvant Chemotherapy for Patients with pT3N0M0 Upper Tract Urothelial Carcinoma.
J Urol. 2015 Aug;194(2):323-9
林口長庚紀念醫院 放射腫瘤科 - A simple risk stratification model that predicts 1-year postoperative mortality rate in patients with solid-organ cancer.
Cancer Med. 2015 Aug 26.
林口長庚紀念醫院 放射腫瘤科 - TGF Beta1 Expression Correlates with Survival and Tumor Aggressiveness of Prostate Cancer.
Ann Surg Oncol. 2015 Ann Surg Oncol. 2015 Dec;22 Suppl 3:1587-93. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - A simple risk stratification model that predicts 1-year postoperative mortality rate in patients with solid-organ cancer.
Cancer Med. 2015 Nov;4(11):1687-96
林口長庚紀念醫院 放射腫瘤科 - Significance of DNMT3b in oral cancer.
PLoS One. 2014 Mar 13;9(3):e89956. ( *co-first author)
林口長庚紀念醫院 放射腫瘤科 - Thrombomodulin expression regulates tumorigenesis in bladder cancer.
BMC Cancer. 2014 May 28;14(1):375. (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - stimation of life expectancy and quality-adjusted life expectancy in non-metastatic nasopharyngeal cancer patients treated by intensity-modulated radiotherapy with or without chemotherapy.
Oral Oncol. 2014 Jul;50(7):646-50
林口長庚紀念醫院 放射腫瘤科 - TGF-β1 mediates the radiation response of prostate cancer.
J Mol Med (Berl). 2014 Sep 18. (* Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus.
Oncotarget. 2014 Sep 30;5(18):8716-28 (Corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Clinical characteristics and treatment outcome in a Taiwanese population of patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma.
Jpn J Clin Oncol. 2014 Dec;44(12):1164-71.
林口長庚紀念醫院 放射腫瘤科 - The role of IL-6 in the radiation response of prostate cancer.
Radiat Oncol. 2013;8:159.
林口長庚紀念醫院 放射腫瘤科 - Outcome of patients with esophageal cancer: a nationwide analysis.
Ann Surg Oncol. 2013;20(9):3023-30.
林口長庚紀念醫院 放射腫瘤科 - IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer.
PLoS One. 2013;8(4):e61901
林口長庚紀念醫院 放射腫瘤科 - Scintigraphic assessment of salivary function after intensity-modulated radiotherapy for head and neck cancer: Correlations with parotid dose and quality of life.
Oral Oncol. 2013;49(1):42-8. (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Role of Interleukin-6 in the Radiation Response of Liver Tumors.
Int J Radiat Oncol Biol Phys. 2012;84(5):e621-30 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Detection of Mucosal Recurrent Nasopharyngeal Carcinomas after Radiotherapy with Narrow-Band Imaging Endoscopy.
Int J Radiat Oncol Biol Phys. 2012;83(4):1213-9.
林口長庚紀念醫院 放射腫瘤科 - Role of DNA methyltransferase 3b in esophageal squamous cell carcinoma.
Cancer, 2012;118(16):4074-89
林口長庚紀念醫院 放射腫瘤科 - Significance of IL-6 in the transition of hormone-resistance prostate cancer and the induction of myeloid derived suppressor cells .
J Mol Med. 2012,;90(11):1343-55 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Comparison of treatment results between surgery alone, preoperative short-course radiotherapy, or long-course concurrent chemoradiotherapy in locally advanced rectal cancer.
Int J Clin Oncol. 2011; in press(* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Significance of the TGF-beta1-IL-6 axis in oral cancer.
Clin Sci. 2012; 122(10):459-72
林口長庚紀念醫院 放射腫瘤科 - Role of DNA methyltransferase 3b in esophageal squamous cell carcinoma.
Cancer, 2012;118(16):4074-89
林口長庚紀念醫院 放射腫瘤科 - Significance of IL-6 in the transition of hormone-resistance prostate cancer and the induction of myeloid derived suppressor cells .
J Mol Med. 2012,;90(11):1343-55 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Expression and function role of DNA methyltransferase 1 in human bladder cancer.
Cancer, 2011;117(22):5221-33. (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - CK2 inhibitors enhance the radiosensitivity of human non-small cell lung cancer cells through inhibition of stat3 activation.
Cancer Biother Radiopharm. 2011;26(3):381-8.
林口長庚紀念醫院 放射腫瘤科 - Incidence and Patterns of Second Primary Malignancies Following Oral Cavity Cancers in a Prevalent Area of Betel-nut Chewing: A Population-based Cohort of 26 166 Patients in Taiwan.
Jpn J Clin Oncol. 2011;41(12):1336-43
林口長庚紀念醫院 放射腫瘤科 - Significance of IL-6 signaling in pharyngeal cancer in its resistance to irradiation and the EGFR inhibitor.
Int J Radiat Oncol Biol Phys, 2010;76(4):1214-24 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - The role of peroxiredoxin I in rectal cancer and related to p53 status.
Int J Radiat Oncol Biol Phys, 2010;78(3):868-78
林口長庚紀念醫院 放射腫瘤科 - Predictive factors of radiation-induced skin toxicity in breast cancer patients.
BMC Cancer. 2010 Sep 23;10:508.
林口長庚紀念醫院 放射腫瘤科 - Role of DNA methyltransferase 1 in hormone-resistant prostate cancer .
J Mol Med. 2010; 88(9):953-62
林口長庚紀念醫院 放射腫瘤科 - Inhibition of corneal neovascularization with plasmid pigment epithelium-derived factor (p-PEDF) delivered by synthetic amphiphile INTeraction-18 (SAINT-18) vector in an experimental model of rat corneal angiogenesis.
Exp Eye Res. 2009
林口長庚紀念醫院 放射腫瘤科 - Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells.
Cancer Gene Therapy, 2009
林口長庚紀念醫院 放射腫瘤科 - Comparison between pre-operative short course radiotherapy and long course chemoradiotherapy in patients with locally advanced rectal cancers.
Therapeutic Radiology and Oncology; 2009,16: 165-177. (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Androgen deprivation modulates the inflammatory response induced by irradiation.
BMC Cancer. 2009, 9:92 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma.
J Mol Med. 2009, 87: 307-320
林口長庚紀念醫院 放射腫瘤科 - Significance of nuclear accumulation of Foxo3a in esophageal squamous cell carcinoma.
Int J Radiat Oncol Biol Phys, 2008, 71:1220-1229(* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Adjuvant concurrent chemoradiotherapy with intensity-modulated pelvic radiotherapy after surgery for high-risk, early stage cervical cancer patients.
Cancer J, 2008,14(3):200-206
林口長庚紀念醫院 放射腫瘤科 - Clinical outcome in post-hysterectomy cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy: comparison with conventional radiotherapy.
Int J Radiat Oncol Biol Phys, 2007; 67: 1438-1444
林口長庚紀念醫院 放射腫瘤科 - The radiation response for hormone- resistant prostate cancer induced by long- term hormone therapy.
Endocrine-Related Cancer, 2007;14:633-645 (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Predictive role of nuclear factor-κB activity in gastric cancer: A promising adjuvant approach with caffeic acid phenethyl ester.
J of Clinical Gastroenterlogy,2007; 41:894-900
林口長庚紀念醫院 放射腫瘤科 - Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression.
Int J Radiat Oncol Biol Phys 2006; 64: 581-91
林口長庚紀念醫院 放射腫瘤科 - The sensitivity of human mesenchymal stem cells to ionizing radiation.
Int J Radiat Oncol Biol Phys 2006; 66: 244-253
林口長庚紀念醫院 放射腫瘤科 - P53 status is a major determinant of the effects of decreasing peroxiredoxin I expression on tumor growth and response of lung cancer cells to treatment.
Int J Radiat Oncol Biol Phys, 2006; 66: 1461-1472
林口長庚紀念醫院 放射腫瘤科 - Differential effects of caffeic acid phenethyl ester for normal lung and lung cancer treated with irradiation: in vitro and in vivo study.
BMC Cancer, 2005;5:158
林口長庚紀念醫院 放射腫瘤科 - Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies.
Head Neck 2005; 27:503-512. (* corresponding author)
林口長庚紀念醫院 放射腫瘤科 - Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells.
J of Radiat Research, 45, 253-260, 2004
林口長庚紀念醫院 放射腫瘤科 - The role of radiotherapy in the treatment of early stage glottic cancer.
Annals of otology, rhinology & laryngology, 2003,10: 904-911
林口長庚紀念醫院 放射腫瘤科