陳裕仁醫師詳細介紹

馬偕紀念醫院總院副院長

馬偕醫院放射腫瘤科資深主治醫師

陽明交通大學醫學院及馬偕醫學大學醫學系教授

中國醫藥學院醫學士

陽明大學博士

台灣放射腫瘤科專科醫師

台灣臨床腫瘤醫學會臨床腫瘤專科醫師

台灣安寧緩和醫學學會專科醫師

台灣頭頸部腫瘤醫學會頭頸腫瘤專科醫師

美國癌症研究學會會員 (AACR)

美國放射腫瘤學會會員 (ASTRO)

馬偕醫護管理專科學校校長

馬偕醫院放射腫瘤科主任

馬偕紀念醫院生醫發展中心暨創新育成中心主任

各種腫瘤之放射治療、安寧療護與精準醫療項目諮詢(癌症或一般型基因檢測、 癌症精準檢測治療等諮詢)

Shin-Yi Liu, Liang-Ting Lin, Chih-Hsien Chang, Yu-Jen Chen* Liposomal 188Rhenium Plus Macrophage Depletion Enhances Anti-PD-L1 Efficacy and B Cell Infiltration Against Lung Metastatic Cancer. Cancer Sci. 2025 Dec;116(12):3442-3458.

Jian-Syun Chen, Chih-Wen Chi, Cheng-Ta Lai, Shu-Hua Wu, Hui-Ru Shieh, Jiin-Cherng Yen*, Yu-Jen Chen* Ciprofloxacin Exerts Anti-Tumor Effects In Vivo Through cGAS-STING Activation and Modulates Tumor Microenvironment. Cells. 2025 Jul 2;14(13):1010.

Yu-Ming Huang, Yi-Shing Leu, Jehn-Chuan Lee, Chao-Hung Chen, Hung-Chang Liu, Chih-Hao Chen, Huan-Chau Lin, Nai-Wen Su, Wen-Chien Huang, Yu-Jen Chen* Simultaneous concurrent chemoradiotherapy and esophagectomy for synchronous head and neck and esophageal squamous cell carcinoma: a retrospective review. Radiat Oncol. 2025 Jul 9;20(1):107.

Wen-Kuei Chang, Yen-Ting Chen, Chin-Ping Lin, Chia-Jung Wang, Hui-Ru Shieh, Chih-Wen Chi, Tung-Hu Tsai*, Yu-Jen Chen* Cordycepin Augments the Efficacy of Anti-PD1 against Colon Cancer. Biomedicines. 2024 Jul 15;12(7):1568.

Wen-Chien Huang, Hung-Tai Wu, Pei-Wen Yang, Chi-Jung Li, Yen-Su Huang, Hang Chang, Yu-Jen Chen* A 35-gene mutation profile predicts the therapeutic outcome of patients with esophageal squamous cell carcinoma receiving neo-adjuvant chemoradiation. Am J Cancer Res. 2024 May 15;14(5):2287-2299.

James Mei-Lin Chan, Yuan-Ching Chang, Hua-Chen Chan, Hsiu-Chuan Chan, Wei-Chin Chang, Liu-Fang Wang, Tung-Hu Tsai, Yu-Jen Chen*, Wen-Chien Huang* FK228 suppress the growth of human malignant pleural mesothelioma tumor independent to epithelioid or non-epithelioid histology. Mol Med. 2024 May 31;30(1):73.

Feng-Chi Kuo, Jerry Cheng-Yen Lai, Hui-Ru Shieh, Wan-Zu Liou, Ming-Jong Bair*, Yu-Jen Chen* Cimetidine Attenuates Therapeutic Effect of Anti-PD-1 and Anti-PD-L1 and Modulates Tumor Microenvironment in Colon Cancer. Biomedicines. 2024 Mar 21;12(3):697.

Lin J-F, Chi C-W, Huang Y-C, Tsai T-H, Chen Y-J. Anti-Cancer Effects of Oxygen-Atom-Modified Derivatives of Wasabi Components on Human Leukemia Cells. International Journal of Molecular Sciences. 2023; 24(7):6823.

Su N-W, Mok L-M, Chan M-L, Liu H-C, Chang W-C, Yun C-H, Shieh T-Y, Wu M-C, Lin H-C, Huang W-C, Chen Y-J. Impact of Perineural Invasion and Preexisting Type 2 Diabetes on Patients with Esophageal Squamous Cell Carcinoma Receiving Neoadjuvant Chemoradiotherapy. Cancers. 2023; 15(4):1122.

Huang Y-M, Hsieh C-H, Wang S-Y, Tsao C-H, Lee J-C, Chen Y-J. Treatment Resulting Changes in Volumes of High-18F-FDG-Uptake Adipose Tissues over Orbit and Epicardium Correlate with Treatment Response for Non-Hodgkin’s Lymphoma. International Journal of Molecular Sciences. 2023; 24(3):2158.

Huang, Y., Wang, T., Chen, M., Lin, C. C., Chang, C. W., Tai, H. C., et al. (2022). Radiomics-based nomogram as predictive model for prognosis of hepatocellular carcinoma with portal vein tumor thrombosis receiving radiotherapy. Front. Oncol. 12:906498.

Huang Y-M, Hsu H-H, Liu C-K, Yang C-K, Tsai P-L, Tang T-Y, Hsu S-M, Chen Y-J. Histopathological and Haemogram Features Correlate with Prognosis in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiation without Pathological Complete Response. Journal of Clinical Medicine. 2022; 11(17):4947.

Cheng Y-Y, Zheng T, Chang MW, Dalley JW, Chen Y-J*, Tsai T-H and Hsieh C-H (2022) Impact of Irradiation on the Pharmacokinetics and Biotransformation of Tamoxifen. Front. Oncol. 12:833108. doi: 10.3389/fonc.2022.833108

Huang, Yu-Ming, Chih-Wen Chi, Pao-Shu Wu, Hung-Chi Tai, Ming-Nan Chien, and Yu-Jen Chen*. 2022. "Adrenal Gland Irradiation Causes Fatigue Accompanied by Reactive Changes in Cortisol Levels" Journal of Clinical Medicine 11, no. 5: 1214.

Peng Tang, Chen Tan, Qingsong Pang, Chih-Wen Chi, Yuwen Wang, Zhiyong Yuan, Yu-Chuen Huang, Yu-Jen Chen. Combination of 35-Gene Mutation Profile and Radiotherapy Dosimetry Predicts the Therapeutic Outcome of Definitive Chemoradiation in Patients With Esophageal Squamous Cell Carcinoma. Front Oncol. 2021 Aug 27;11:729418.

Che-Wei Su, Jehn-Chuan Lee, Yi-Fang Chang, Nai-Wen Su, Pei-Hsuan Lee, Kun-Yao Dai, Hung-Chi Tai, Yi-Shing Leu, Yu-Jen Chen. Delta-volume radiomics of induction chemotherapy to predict outcome of subsequent chemoradiotherapy for locally advanced hypopharyngeal cancer. Tumori. 2021 Aug 21;3008916211039018. doi: 10.1177/03008916211039018. Online ahead of print.

Tai H-C, Lee J, Huang W-C, Liu H-C, Chen C-H, Huang Y-C, Lee C-J, Yun C-H, Hsu S-M, Chen Y-J. The Impact of Radiation to Epicardial Adipose Tissue on Prognosis of Esophageal Squamous Cell Carcinoma Receiving Neoadjuvant Chemoradiotherapy and Esophagectomy. Applied Sciences. 2021; 11(9):4023.

Chang CW, Lee HC, Li LH, Chiang Chiau JS, Wang TE, Chuang WH, Chen MJ, Wang HY, Shih SC, Liu CY, Tsai TH, Chen YJ*. Fecal microbiota transplantation prevents intestinal injury, upregulation of toll-like receptors, and 5-fluorouracil/oxaliplatin-induced toxicity in colorectal cancer. Int J Mol Sci. 2020; Jan 21(2): 386.

Liu SY, Huang WC, Yeh HI, Ko CC, Shieh HR, Hung CL, Chen TY, Chen YJ*. Sequential blockade of PD-1 and PD-L1 causes fulminant cardiotoxicity-from case report to mouse model validation. Cancers. 2019; Apr 11(4): 580.

Su NW, Wu SH, Chi CW, Tsai TH, Chen YJ*. Cordycepin, isolated from medicinal fungus Cordyceps sinensis, enhances radiosensitivity of oral cancer associated with modulation of DNA damage repair. Food Chem Toxicol. 2019; Feb 124: 400-410.

Liu YM, Liu YK, Huang PI, Tsai TH, Chen YJ*. Antrodia cinnamomea mycelial fermentation broth inhibits the epithelial-mesenchymal transition of human esophageal adenocarcinoma cancer cells. Food Chem Toxicol. 2018; Sep 119: 380-386.

Liu CK, Chen CA, LeeTY, Chang HH, Liao HF, Chen YJ*. Rice protein prolamin promotes anti-leukemia immunity and inhibits leukemia growth in vivo. Food Chem Toxicol. 2018; Feb 112: 435-440.

Chang CH, Liu SY, Chi CW, Yu HL, Chang TJ, Tsai TH, Lee TW, Chen YJ*. External beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics. Int J Nanomed. 2015; May 10: 3641-3649.

Liao HF, Cheng AJ, Huang HT, Shen ML, Hei TK, Chen YJ*. Nuclear factor-kappaB as a switch in regulation of resveratrol-mediated apoptosis and erythrocytic differentiation in human leukemia cells. Food Chem. 2012; Jun 132(4): 2094-2101.

Chen YJ, Lin CP, Hsu ML, Shieh HR, Chao NK, Chao KSC. Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner. Int J Radiat Oncol. 2011; Jul 80(3): 851-859.

Chen YJ, Huang WP, Yang YC, Lin CP, Chen SH, Hsu ML, Tseng YJ, Shieh HR, Chen YY, Lee JJ. Platonin induces autophagy-associated cell death in human leukemia cells. Autophagy 2009; Feb 5(2): 173-183.