學歷
The Scripps Research Institute, Cell and Molecular Biology博士
陽明大學醫學系醫學士
經歷
台北榮民總醫院內科部住院醫師
陽明大學附設醫院住院醫師、主治醫師
衛生福利部立金門醫院主治醫師
台北榮民總醫院腫瘤醫學部總醫師、主治醫師
陽明大學醫學系助理、臨床醫學研究所助理教授
現職
台北榮民總醫院 腫瘤醫學部 主治醫師
國立陽明交通大學 臨床醫學研究所 助理教授
行天宮醫療志業醫療財團法人恩主公醫院 血液腫瘤科 兼任主治醫師
專長
一般腫瘤學
乳癌
泌尿癌 (腎癌, 膀胱癌, 攝護腺癌)
分子生物學
癌症臨床試驗
學會/資格/其他
台灣內科醫學會內科專科執照(No.8322)
中華民國癌症醫學會腫瘤內科專科醫師 (No.1589)
美國醫師證書 (ECFMG certificate)
著作
Jiun-I Lai, Ta-Chung Chao, Chun-Yu Liu, Chi-Cheng Huang, Ling-Ming Tseng. A Systemic Review of Taxanes and Their Side Effects in Metastatic Breast Cancer. Frontiers in Oncology, 2022 (Accepted, in press)
ChihYi Lin, Chung-Jen Yu, Chia-I Shen, Chun-Yu Liu, Ta-Chung Chao, Chi-Cheng Huang, Ling-Ming Tseng, Jiun-I Lai. IKZF3 amplification frequently occurs in HER2 positive breast cancer and is a potential therapeutic target. Medical Oncology 2022 (accepted, in press)
Chih-Yi Lin, Chung-Jen Yu, Chun-Yu Liu, Ta-Chung Chao, Chi-Cheng Huang, Ling-Ming Tseng, Jiun-I Lai. CDK4/6 inhibitors downregulate the ubiquitin conjugating enzymes UBE2C/S/T involved in the ubiquitin–proteasome pathway in ER+ breast cancer. Clinical and Translational Oncology 2022 Aug 2. doi: 10.1007/s12094-022-02881-0
Tang CY, Hang JF, Hung YP, Chiu NC, Lai JI, Chen MH, Liu CY, Yang MH, Chao Y, Chang PM. A generational comparison for unfavorable cancer of unknown primary in a single institute over 20 years. Cancer Med. 2022 Jul 3. doi: 10.1002/cam4.4960
Huang CC, Tsai YF, Liu CY, Lien PJ, Lin YS, Chao TC, Feng CJ, Chen YJ, Lai JI, Phan NN, Hsu CY, Chiu JH, Tseng LM. Prevalence of Tumor Genomic Alterations in Homologous Recombination Repair Genes Among Taiwanese Breast Cancers. Ann Surg Oncol. 2022 Jun;29(6):3578-3590
Lai JI, Tseng YJ, Chen MH, Huang CF, Chang PM. Clinical Perspective of FDA Approved Drugs With P-Glycoprotein Inhibition Activities for Potential Cancer Therapeutics. Front Oncol. 2020 Nov 16;10:561936
Tan KT, Yeh CN, Chang YC, Cheng JH, Fang WL, Yeh YC, Wang YC, Hsu DS, Wu CE, Lai JI, Chang PM, Chen MH, Lu ML, Chen SJ, Chao Y, Hsiao M, Chen MH. PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy. J Immunother Cancer. 2020 Mar;8(1):e000485
Chang SC, Lai YC, Chang CY, Huang LK, Chen SJ, Tan KT, Yu PN, Lai JI. Concomitant Genetic Alterations are associated with worse clinical outcome in EGFR mutant NSCLC patients treated with tyrosine kinase inhibitors. (Corresponding Author) Transl Oncol. 2019 Aug 8;12(11):1425-1431. doi: 10.1016/j.tranon.2019.07.008.
Jiun-I Lai, Abhinav K. Reddy, Justin Y. Newberg, Meagan Montesion, Peter Mu-Hsin Chang. High-grade salivary gland ductal carcinoma with unusual EGFR amplification responsive to afatinib. JCO Precis Oncol. 2019 Dec;3:1-5. doi: 10.1200/PO.19.00186.
Chen MH, Chang SC, Lin PC, Yang SH, Lin CC, Lan YT, Lin HH, Lin CH, Lai JI, Liang WY, Lu ML, Yang MH, Chao Y. Combined Microsatellite Instability and Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) Might Be a More Promising Immune Biomarker in Colorectal Cancer. 2019 Jul 10. pii: theoncologist.2019-0171.
Chiu, Yu-Hui, Lai, Jiun-I, Tseng, Chia-Ying,Wang, Shih-Hao,Li, Li-Hua,Kao, Wei-Fong,How, Chorng-Kuang ,Chang, Wen-Han ,Hsieh, Chin-Yi. Impact of angiotension I converting enzyme gene I/D polymorphism on running performance, lipid, and biochemical parameters in ultra-marathoners. (Co-first author) Medicine (Baltimore). 2019 Jul;98(29):e16476.
Jiun-I Lai, Daniel Nachun, Lina Petrosyan, Benjamin Throesch, Erica Campau, Fuying Gao, Kristin K Baldwin, Giovanni Coppola, Joel M. Gottesfeld, Elisabetta Soragni. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. J Biol Chem. 2019 Feb 8;294(6):1846-1859. doi: 10.1074/jbc.RA118.006515.
Chang SC, Lai JI, Lu MC, Lin KH, Wang WS, Lo SS, Lai YC. Reduction in the incidence of pneumonia in elderly patients after hip fracture surgery: An inpatient pulmonary rehabilitation program. Medicine (Baltimore). 2018 Aug;97(33):e11845
Chang SC, Lai YC, Chen YC, Wang NK, Pan JN, Wang WS, Lai JI. (Corresponding Author) CBX3/heterochromatin protein 1 gamma is significantly upregulated in patients with non-small cell lung cancer. Asia-Pacific Journal of Clinical Oncology, 2017 Nov 10. doi: 10.1111/ajco.12820.
Liu CH, Tseng YF, Lai JI, Chen YQ, Wang SH, Kao WF, Li LH, Chiu YH, How CK, Chang WH. The Changes of Red Blood Cell Viscoelasticity and Sports Anemia in Male 24-hr Ultra-marathoners. J Chin Med Assoc 2018 May;81(5):475-481. doi: 10.1016/j.jcma.2017.09.011
Lai JI, Lai YC, Chen YC, Wang NK, Pan JN, Wang WS, Chang SC. Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation. Cancer Gene Ther. 2017 Sep;24(9):373-380. doi: 10.1038/cgt.2017.26.
Lai JI, Leman LJ, Ku S, Vickers CJ, Olsen CA, Montero A, Ghadiri MR, Gottesfeld JM.Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3289-3293. doi: 10.1016/j.bmcl.2017.06.027.